Low-Dose Lithium for Improving Mental Health

A Double-Blind, Placebo-Controlled, Crossover Study of Low-Dose Lithium in Personality Disorder Diagnosed Patients with Elevated Inflammatory Biomarkers.

About Low-Dose Lithium and the (LIP) Study

Meet the Research Team







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What is Low-Dose Lithium?

In low doses, lithium can improve various mental health conditions and acts as a natural anti-inflammatory. Lithium is a naturally occurring mineral found in our food and water. As a metal and salt that conducts and stores energy in the brain, increasing natural lithium levels can better distribute neuronal energy and inhibit aging enzymes like GSK-3. Balanced energy promotes a positive mood, supports the brain’s detoxification process, and enhances overall emotional wellness.

What Does Low-Dose Lithium Treat?

Standard lithium prescriptions typically range from 600 to 1200 milligrams daily and are often used to treat bipolar disorder or schizophrenia. However, doses as low as one milligram of elemental lithium can be beneficial, regardless of your mental health challenges. Low-dose lithium can help treat: – Post-Covid-19 symptoms – Alzheimer’s disease and its prevention – Mood disorders – Cognitive decline – Addiction or overuse of alcohol, cannabis, nicotine, and benzodiazepines – Suicidal thoughts – Anxiety – Stress – Self-destructive behavior – Depression – Sleep issues (difficulty falling and staying asleep) – Aggression – Impulsivity Lithium supports the brain’s aging process, improves cardiovascular health, musculoskeletal function, metabolic health, and aids in inflammatory and antioxidant processes.

How does low-dose lithium treatment work?


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LIP Study News & Announcements


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Read the Lithium Inflammation Psychiatry (LIP) Study (PDF)

A Double-Blind, Placebo-Controlled, Crossover Study.


Read the Full LIP Study (PDF)


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Health Effects of Low-Dose Lithium: A Systematic Review

See the latest Articles and Posts about the LIP Study.


Mental Health & Low-Dose Lithium


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Low-Dose Lithium Research Team from the Karolinska Institute

Personality Disorder Research Team from the Karolinska Institute


Meet the Researchers